The spirit of philanthropy lies at the foundation of the teaching affiliates of
School . Similarly, the Transplantation Research Center (TRC) has been the recipient of significant gifts, particularly from the Schuster family. However, much work remains to be done and gifts of all sizes fuel the Center’s forward march – its search for innovative new therapies, its quest to improve patient care and its commitment to train the next generation of outstanding health care professionals.
The power of giving is often immeasurable. Outright gifts of cash, appreciated assets and real estate immediately go to work for TRC, helping to sustain and improve patient programs, facilities and teaching efforts. Planned gifts give donors the opportunity to make a future gift to the hospital while reaping the rewards during your lifetime.
A primary focus of the clinical and research efforts will be to encourage a “multi-pronged” approach to patient care, integrating the expertise of kidney and liver specialists, surgeons, oncologists, cardiologists, dermatologists, endocrinologists, and immunologists. Clinical approaches must be implemented hand-in-hand with research-driven goals that will ultimately improve current practices.
We ask that you coordinate your giving plan with either the Brigham and Women’s Hospital Development Office or the Children’s Hospital Trust.
Clinical Recruitment: Endowment to provide the Director flexibility to focus on the Transplantation Research Center’s recruitment needs. Over the next three to five years, recruitment will be one of the most pressing priorities to expand the TRC. Recruitment plans to promote research efforts are proceeding on several fronts: junior faculty to be recruited from outside BWH and CHB; surgical faculty, including a transplantation surgeon who will focus solely on clinical practice, and an additional member of the tissue typing team.
Microsystems engineering in medicine and regenerative medicine: There is significant need for funds to recruit leaders in the growing areas of micro- and mono-engineering as applied to medicine. A great deal of competition exists for such investigators due to the increasingly prominent rise of biomedical engineering departments worldwide. Progress in stem cell research and regenerative medicine in general requires a strong collaboration between physicians and engineers. For example, engineers might produce patterned substrates to which liver, kidney, or heart cells will adhere and establish functional characteristics that will replace the failed function of the native organs.
Comprehensive Clinical Care Initiative: Funding to promote clinical and surgical collaboration, and a multi-specialty program for patients focusing on complete care of the transplant recipient in a way that will optimize translation of research findings and improve outcomes. Funding needs include infrastructure, salaries, supplies, equipment, etc. Patient Management Database: The creation of the Transplantation Research Center may, in the short term, increase practice overhead costs because it will require that patients spend longer periods of time in the clinic. More personnel will be needed to improve patient education, database management, and clinical services. The long-term benefit of this effort, however, will be reduced costs as patient volume increases, and clinical research attracts more grant funding. Moreover, the Center’s reputation for excellence in kidney and transplantation care will benefit the institution as a whole.
BASIC SCIENCE PROGRAMS
The Discovery and Opportunity Fund: To provide support to pursue a promising new line of research or a project that may not yet be eligible for NIH funding, recruit staff, or promote collaborative efforts. Current use funding will be instrumental in addressing the Center’s most pressing needs. Pediatric Transplant Research Funds: Flexible funding to pursue new avenues of pediatric transplantation study and promote collaborative efforts within the Center’s pediatric faculty and researchers in the broader Harvard community.
Patient Information Gateway: To support the creation and staffing of an online resource for patients and physicians on transplantation medicine, including clinical trial data, treatment options, journal articles and publications, and disease information. Equipment: New equipment is needed to support the research efforts of current and new staff. For example, we are currently pursuing the acquisition of a flow cytometer with cell sorter and a Luminex multiplex analysis system. This instrumentation will greatly enhance the capabilities of Center faculty, the entire renal division, and the wider research community. Organ Funds: To speed research focusing on microsystems engineering and regenerative medicine with the goal of applying advanced technology to the development of new organs. Start-up funding is needed to support this collaborative effort that will require expertise from biological, chemical, engineering, and surgical disciplines.
Transplant Fellowships: To provide advanced clinical trainees the opportunity to focus on issues and problems associated with caring for transplant patients. Current nephrology fellowships do not include time or training for young physicians to concentrate on transplant medicine. Current use fellowships of $50K per fellow annually are needed. Transplant Education Fund: To support physician training through “virtual patient” scenarios, teaching materials library, and pathology slides to improve trainee’s “real life” training experience. Endowed funds start at $50K. Transplant Medicine Symposia: To promote information exchange, best practices, and encourage communication between different areas of transplant medicine. May include visiting professorships and sponsored lectures.